Cancer Genomics and Epigenetics
Cancer genomics and epigenetics explore how genetic mutations and changes in gene expression without altering DNA sequences contribute to cancer development. Genomic studies reveal key mutations, amplifications, or deletions in cancer-driving genes, enabling targeted therapies. Epigenetic mechanisms like DNA methylation and histone modification regulate gene activity and can be disrupted in cancer. These insights help identify diagnostic markers, treatment targets, and resistance mechanisms. Integrating genomics and epigenetics into clinical practice is advancing precision oncology, allowing early detection, prognosis prediction, and more effective, individualized treatment strategies to manage and potentially cure various types of cancer.