Cancer Therapy & Radiation Oncology

Targeted Therapies Combined with Radiation

The integration of targeted therapies with radiation therapy represents a powerful strategy to enhance tumor control. This session focuses on combining radiotherapy with molecularly targeted agents, including tyrosine kinase inhibitors, PARP inhibitors, and immune checkpoint inhibitors. Experts will discuss the biological rationale behind radiosensitization, tumor microenvironment modulation, and synergistic treatment sequencing. Clinical trial data will highlight improved outcomes in lung, breast, head and neck, and gastrointestinal cancers. Attention will also be given to toxicity management, optimal dosing schedules, and biomarkers predicting response. Emerging strategies such as combining radiation with antibody-drug conjugates and next-generation immunotherapies will be explored. This session underscores the importance of multidisciplinary collaboration between radiation oncologists, medical oncologists, and translational researchers to maximize therapeutic benefit while maintaining patient safety.