Clinical Trials in Advanced Radiation Therapy

Clinical trials are essential for validating innovative radiation technologies and treatment protocols. This session examines ongoing and completed trials evaluating proton therapy, adaptive radiotherapy, hypofractionation, and combination regimens with immunotherapy. Experts will discuss trial design, endpoint selection, patient stratification, and incorporation of patient-reported outcomes. Emphasis will be placed on biomarker-driven trials and real-world evidence generation to accelerate clinical translation. International collaboration is crucial to expanding enrollment and ensuring diverse representation. Ethical considerations, regulatory pathways, and funding challenges will also be explored. By fostering robust clinical research, the radiation oncology community continues to refine standards of care and improve global treatment outcomes.

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