Cancer Therapy & Radiation Oncology

Radiogenomics and Personalized Cancer Treatment

Radiogenomics is transforming cancer therapy by linking genomic information with radiation response and toxicity prediction. This session explores how molecular profiling and genetic biomarkers guide individualized radiation dose selection, fractionation strategies, and treatment combinations. Speakers will discuss advances in tumor genomics, DNA repair pathway mutations, radiosensitivity signatures, and predictive modeling. Integrating radiogenomic data into clinical workflows enables clinicians to tailor treatments based on patient-specific biological characteristics rather than standardized protocols. The session will also examine large-scale genomic databases, machine learning applications, and translational research bridging laboratory discoveries with clinical implementation. Ethical considerations, data sharing challenges, and global access to precision diagnostics will be addressed. By leveraging genetic insights, radiogenomics enhances therapeutic efficacy while minimizing normal tissue toxicity. This personalized approach supports improved survival outcomes and aligns with the broader shift toward precision oncology worldwide.