Chemotherapy

Cancer chemotherapy involves the selection of drugs and dose levels, which will eradicate disseminated cancer cells, without causing severe host toxicity. Depending on the primary location and the extension of the disease, chemotherapy can be curative or palliative. In the majority of cases, Chemotherapy leads to the prolongation of survival, and in other cases it results in the eradication of the disease. Chemotherapy can be in most cases a major adjuvant to surgical therapy and/or radiotherapy. It is most successful against Leukemias. Mechanism-based approaches have also been explored for several decades. About 30 chemotherapeutic drugs are in regular use in the treatment of cancer till date. All Antitumor drugs may be placed into one of three classes based on the relationship of the effect to the mitotic cycle of the cell:

1. Cell cycle active, phase specific

2. Cell cycle active, phase non-specific

3. Non-cell cycle active.

  • Types of Chemotherapy
  • Combination Chemotherapy
  • Cancer Chemotherapy Side Effects
  • Cancer Chemotherapy Resistance

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