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Lecio Leonardo Luvezuti

Lecio Leonardo Luvezuti

National Institute of Cancer, Brazil

Title: Comparison of 3DCRT, IMRT sliding window, VMAT techniques in radiotherapy treatments of distal esophageal cancer

Biography

Biography: Lecio Leonardo Luvezuti

Abstract

The objective of this study was to compare three techniques of radiotherapy treatments, with correction of heterogeneities, in seven patients diagnosed with distal esophageal cancer: IMRT with seven co-planar fields evenly distributed at equal intervals, VMAT composed of two arcs of 359.8º and 3DCRT with four co-planar fields (two antero-posterior and two oblique). This study is retrospective and evaluated the treatments regarding PTV coverage, Paddick conformity index, monitor units, heterogeneity index and dose-volume parameters in organs at risk. The IMRT and VMAT plans reduced the irradiated lung volume with the 20 Gy dose (V20lung) and, consequently, the mean dose in the lung (Dlung). The mean reductions with the IMRT and VMAT techniques in relation to 3DCRT for V20lung were, respectively, 5.69% and 5.72%. Regarding the parameter (Dlung), the reduction was of 1.59 Gy and 1.26 Gy, respectively. The IMRT and VMAT techniques also showed better dose conformity values in the target volume. There was a significant dose reduction in critical organs (spinal cord and heart) in relation to 3DCRT plans. Thus, the lung volume exposed to radiation can be reduced with IMRT and VMAT and the dose prescribed and the dose prescribed for this type of treatment can be escalated, but future clinical studies that confirm this hypothesis are still necessary.